USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: SORCN_HUMAN USC-OGP 2-DE database:  SORCN_HUMAN SORCN_HUMAN General information about the entry View entry in simple text format Entry name SORCN_HUMAN Primary accession number P30626 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Sorcin; AltName: Full=22 kDa protein; AltName: Full=CP-22; Short=CP22; AltName: Full=V19;. Gene name Name=SRI Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0570: pI=5.06; Mw=20070 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0835: pI=5.05; Mw=19965 Cross-references UniProtKB/Swiss-Prot P30626; SORCN_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SORCN_HUMAN Primary accession number P30626 Secondary accession number(s) A8MTH6 B4DKK2 D6W5Q0 Sequence was last modified on  April 1, 1993 (version 1) Annotations were last modified on  March 15, 2017 (version 180) Name and origin of the protein Description RecName: Full=Sorcin; AltName: Full=22 kDa protein; AltName: Full=CP-22; Short=CP22; AltName: Full=V19; Gene name Name=SRI Encoded on Name=SRI Keywords 3D-structure; Alternative splicing; Calcium; Complete proteome; Cytoplasm; Direct protein sequencing; Membrane; Metal-binding; Reference proteome; Repeat; Sarcoplasmic reticulum. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L12387; AAA92155.1; -; mRNA EMBL M32886; AAA60588.1; -; mRNA EMBL AK296601; BAG59214.1; -; mRNA EMBL BM739144; -; NOT_ANNOTATED_CDS; mRNA EMBL AC003991; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC005075; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471091; EAW76909.1; -; Genomic_DNA EMBL CH471091; EAW76910.1; -; Genomic_DNA EMBL BC011025; AAH11025.1; -; mRNA CCDS CCDS47638.1; -. [P30626-2]; . CCDS CCDS5612.1; -. [P30626-1]; . CCDS CCDS59063.1; -. [P30626-3]; . PIR S52094; S52094; . RefSeq NP_001243820.1; NM_001256891.1; . RefSeq NP_001243821.1; NM_001256892.1. [P30626-3]; . RefSeq NP_003121.1; NM_003130.3. [P30626-1]; . RefSeq NP_944490.1; NM_198901.1. [P30626-2]; . UniGene Hs.489040; -; . PDB 1JUO; X-ray; 2.20 A; A/B=1-198 PDB 2JC2; X-ray; 2.50 A; A/B/C/D=1-198 PDB 4U8D; X-ray; 2.30 A; A/B=1-198 PDB 4UPG; X-ray; 2.10 A; A=30-198 PDB 4USL; X-ray; 1.65 A; A=1-198 D=1-32 PDBsum; 1JUO; -; . PDBsum 2JC2; -; . PDBsum 4U8D; -; . PDBsum 4UPG; -; . PDBsum 4USL; -; . ProteinModelPortal P30626; -; . SMR P30626; -; . BioGrid 112595; 37; . DIP DIP-40970N; -; . IntAct P30626; 15; . MINT MINT-4999795; -; . STRING 9606.ENSP00000265729; -; . iPTMnet P30626; -; . PhosphoSitePlus P30626; -; . SwissPalm P30626; -; . BioMuta SRI; -; . DMDM 267021; -; . OGP P30626; -; . EPD P30626; -; . MaxQB P30626; -; . PaxDb P30626; -; . PeptideAtlas P30626; -; . PRIDE P30626; -; . TopDownProteomics P30626-1; -. [P30626-1]; . Ensembl ENST00000265729; ENSP00000265729; ENSG00000075142. [P30626-1]; . Ensembl ENST00000394641; ENSP00000378137; ENSG00000075142. [P30626-2]; . Ensembl ENST00000431660; ENSP00000391148; ENSG00000075142. [P30626-3]; . GeneID 6717; -; . KEGG hsa:6717; -; . UCSC uc003ujq.3; human. [P30626-1]; . CTD 6717; -; . DisGeNET 6717; -; . GeneCards SRI; -; . HGNC HGNC:11292; SRI; . HPA HPA019004; -; . HPA HPA073666; -; . MIM 182520; gene; . neXtProt NX_P30626; -; . OpenTargets ENSG00000075142; -; . PharmGKB PA36117; -; . eggNOG KOG0037; Eukaryota; . eggNOG ENOG410YKQK; LUCA; . GeneTree ENSGT00620000087734; -; . HOGENOM HOG000231982; -; . HOVERGEN HBG004492; -; . InParanoid P30626; -; . OMA GQQGVVN; -; . OrthoDB EOG091G0ISY; -; . PhylomeDB P30626; -; . TreeFam TF314682; -; . Reactome R-HSA-2672351; Stimuli-sensing channels; . Reactome R-HSA-418359; Reduction of cytosolic Ca++ levels; . Reactome R-HSA-425561; Sodium/Calcium exchangers; . Reactome R-HSA-5578775; Ion homeostasis; . Reactome R-HSA-936837; Ion transport by P-type ATPases; . SIGNOR P30626; -; . ChiTaRS SRI; human; . EvolutionaryTrace P30626; -; . GeneWiki SRI_(gene); -; . GenomeRNAi 6717; -; . PRO PR:P30626; -; . Proteomes UP000005640; Chromosome 7; . Bgee ENSG00000075142; -; . CleanEx HS_SRI; -; . ExpressionAtlas P30626; baseline and differential; . Genevisible P30626; HS; . GO GO:0030424; C:axon; IEA:Ensembl; . GO GO:0043679; C:axon terminus; IEA:Ensembl; . GO GO:0005737; C:cytoplasm; TAS:UniProtKB; . GO GO:0005829; C:cytosol; IDA:BHF-UCL; . GO GO:0044326; C:dendritic spine neck; IEA:Ensembl; . GO GO:0005789; C:endoplasmic reticulum membrane; IDA:BHF-UCL; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:BHF-UCL; . GO GO:0005739; C:mitochondrion; IEA:Ensembl; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0016529; C:sarcoplasmic reticulum; TAS:BHF-UCL; . GO GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell; . GO GO:0005790; C:smooth endoplasmic reticulum; IEA:Ensembl; . GO GO:0030315; C:T-tubule; TAS:BHF-UCL; . GO GO:0030018; C:Z disc; IDA:BHF-UCL; . GO GO:0005246; F:calcium channel regulator activity; TAS:ProtInc; . GO GO:0005509; F:calcium ion binding; IDA:BHF-UCL; . GO GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:GO_Central; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0044325; F:ion channel binding; TAS:BHF-UCL; . GO GO:0002020; F:protease binding; IPI:BHF-UCL; . GO GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL; . GO GO:0005102; F:receptor binding; TAS:ProtInc; . GO GO:0001508; P:action potential; TAS:ProtInc; . GO GO:0006816; P:calcium ion transport; IEA:Ensembl; . GO GO:0042994; P:cytoplasmic sequestering of transcription factor; IEA:Ensembl; . GO GO:0007507; P:heart development; TAS:ProtInc; . GO GO:0006880; P:intracellular sequestering of iron ion; TAS:ProtInc; . GO GO:0007517; P:muscle organ development; TAS:ProtInc; . GO GO:0010459; P:negative regulation of heart rate; IMP:BHF-UCL; . GO GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL; . GO GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IEA:Ensembl; . GO GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl; . GO GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl; . GO GO:0006508; P:proteolysis; IBA:GO_Central; . GO GO:0051924; P:regulation of calcium ion transport; IMP:BHF-UCL; . GO GO:0086004; P:regulation of cardiac muscle cell contraction; IMP:BHF-UCL; . GO GO:0010649; P:regulation of cell communication by electrical coupling; TAS:BHF-UCL; . GO GO:1901844; P:regulation of cell communication by electrical coupling involved in cardiac conduction; IMP:BHF-UCL; . GO GO:0008016; P:regulation of heart contraction; TAS:ProtInc; . GO GO:1901841; P:regulation of high voltage-gated calcium channel activity; IMP:BHF-UCL; . GO GO:1901077; P:regulation of relaxation of muscle; IMP:BHF-UCL; . GO GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; TAS:BHF-UCL; . GO GO:0006942; P:regulation of striated muscle contraction; TAS:ProtInc; . GO GO:0007165; P:signal transduction; TAS:UniProtKB; . GO GO:0006810; P:transport; TAS:ProtInc; . CDD cd00051; EFh; 3; . Gene3D 1.10.238.10; -; 1; . InterPro IPR011992; EF-hand-dom_pair; . InterPro IPR018247; EF_Hand_1_Ca_BS; . InterPro IPR002048; EF_hand_dom; . Pfam PF13405; EF-hand_6; 1; . Pfam PF13833; EF-hand_8; 1; . SMART SM00054; EFh; 2; . SUPFAM SSF47473; SSF47473; 1; . PROSITE PS00018; EF_HAND_1; 2; . PROSITE PS50222; EF_HAND_2; 4; .

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